Description
Selank (TP-7, CAS 129954-34-3) is a synthetic heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, developed by the Institute of Molecular Genetics of the Russian Academy of Sciences as a structurally extended analog of tuftsin – a naturally occurring immunomodulatory tetrapeptide derived from the Fc region of immunoglobulin G – supplied by AusPepLabs in lyophilized format for laboratory and analytical research applications. The Pro-Gly-Pro C-terminal extension was added to enhance metabolic stability compared to native tuftsin. Selank is studied as a research tool for investigating GABAergic neurotransmission modulation, BDNF pathway dynamics, serotonin system interactions, and neuroimmune signaling in controlled preclinical experimental systems. Each vial is independently verified to ≥99% HPLC purity with a Certificate of Analysis available on request. For scientific research use only.
Why Research Laboratories Select Selank
Selank is a unique research tool that combines tuftsin-derived immunomodulatory properties with neuromodulatory signaling activity across GABAergic, serotonergic, and BDNF pathways – making it one of the few synthetic heptapeptides with multi-system neuroimmune research applications. Its Pro-Gly-Pro C-terminal extension significantly enhances metabolic stability compared to native tuftsin, enabling longer-duration experimental protocols and more consistent assay conditions across repeated measurements.
- Synthetic tuftsin analog – Thr-Lys-Pro-Arg core extended with Pro-Gly-Pro for enhanced metabolic stability
- Studied for GABAergic neurotransmission modulation in rodent anxiety and stress response research models
- Studied for BDNF upregulation in hippocampal and cortical cell-based research systems
- Studied for serotonin (5-HT) system stabilization in preclinical neurochemistry research models
- Enkephalinase inhibition studied in preclinical opioid withdrawal and endogenous opioid pathway research
- Immunomodulatory activity studied via cytokine pathway interactions in neuroimmune research models
- Approved pharmaceutical equivalent in Russia and Ukraine – extensive published literature available
- Lyophilized format ensures stability and reproducibility across experimental runs

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