MOTS-C

Description

MOTS-C (CAS: 1627580-64-6) (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16 amino acid mitochondrial-derived peptide (MDP) supplied by AusPepLabs for laboratory and analytical research applications. First formally characterized in a landmark 2015 study published in Cell Metabolism, MOTS-C is encoded within the mitochondrial 12S rRNA gene. Each vial is independently verified to ≥99% HPLC purity with a Certificate of Analysis available on request. For scientific research use only.

Why Research Laboratories Select MOTS-C

MOTS-C is among the most studied mitochondrial-derived peptides in current metabolic and cellular biology research. As a peptide encoded by mitochondrial DNA but translated in the cytoplasm, it represents a unique class of signaling molecules that have drawn significant scientific interest since its initial characterization in 2015.

• Unique mitochondrial-derived peptide – encoded by mtDNA, translated in the cytoplasm
• 16 amino acid sequence highly conserved across 14 species including humans and mice
• Studied in the context of AMPK pathway activation in preclinical metabolic research models
• Referenced in peer-reviewed literature including Cell Metabolism, Scientific Reports, and Geroscience
• Relevant to laboratory research on mitochondrial signaling, cellular stress response, and metabolic pathways
• Lyophilized format ensures stability and reproducibility across experimental runs